Dr Fraz Mir
Dr Fraz Mir
Position(s):
Associate Lecturer in Medicine, University of Cambridge;
Consultant Physician - Clinical Pharmacology and Acute/General Medicine, Cambridge University Hospitals NHS Foundation Trust.
Email: fam31@cam.ac.uk
Tel: 01223 348342
Websites: http://www.cambsems.org;
http://www.colourmed.com
Research Description
My main research interests are in co-ordinating large multi-centre randomised-controlled trials locally, in collaboration with Sylvia Blackwood. We are one of the largest national recruiting centres for the HPS2-THRIVE study which is looking at the effect of niacin on the prevention of cardiovascular outcomes in high risk patients. We also hope to be a major centre for HPS3-REVEAL when the study is launched in Summer 2011. This will investigate the role of increasing serum HDL by use of the drug anacetrapib. Furthermore, we hope to be involved in the CHIPS study which aims to determine treatment targets for pregnant women.
In addition, I am collaborating with a number of colleagues to explore the mechanisms via which anti-cancer agents cause cardiovascular problems such as hypertension and their treatment.
Current Research Support
CTSU, University of Oxford
Recent Publications
Clarke R, Halsey J, Lewington S, Lonn E, Armitage J, Manson JE, Bønaa KH, Spence JD, Nygård O, Jamison R, Gaziano JM, Guarino P, Bennett D, Mir F, Peto R, Collins R; B-Vitamin Treatment Trialists' Collaboration.
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med. 2010 Oct 11;170(18):1622-31Spalding JA, Cole BL, Mir FA.
Advice for medical students and practitioners with colour vision deficiency: a website resource. Clin Exp Optom. 2010 Jan;93(1):39-41.-
Hickson SS, Butlin M, Mir FA, Graggaber J, Cheriyan J, Khan F, Grace AA, Yasmin, Cockcroft JR, Wilkinson IB, McEniery CM; Anglo-Cardiff Collaboration Trial Investigators.
The accuracy of central SBP determined from the second systolic peak of the peripheral pressure waveform. J Hypertens. 2009;27:1784-8. -
Mir FA, Brown MJ, Appleton DS.
Lessons in the diagnosis and management of Conn's syndrome. J Clin Med. 2007 Oct;7(5):530-1. Campbell JL, Griffin L, Spalding JA, Mir FA.
The effect of abnormal colour vision on the ability to identify and outline coloured clinical signs and to count stained bacilli in sputum. Clin Exp Optom. 2005 Nov;88(6):376-81.Campbell JL, Spalding JA, Mir FA.
The description of physical signs of illness in photographs by physicians with abnormal colour vision. Clin Exp Optom. 2004 Jul;87(4-5):334-8.-
Mir FA, Wilkinson IB.
A rational approach to hypertension. Practitioner. 2004 Mar;248(1656):176, 179, 182-9 passim. -
Campbell JL, Spalding AJ, Mir FA, Birch J.
Doctors and the assessment of blood glucose testing sticks: does colour blindness matter? Br J Gen Pract. 2000 May;50(454):393-5. -
Campbell JL, Spalding AJ, Mir FA, Birch J.
Doctors and the assessment of clinical photographs--does colour blindness matter? Br J Gen Pract. 1999 Jun;49(443):459-61.